Correction: Attenuation of High-Frequency (50-200 Hz) Thalamocortical EEG Rhythms by Propofol in Rats Is More Pronounced for the Thalamus than for the Cortex
نویسندگان
چکیده
There is an error in the second sentence of the Results section in the Abstract. The correct sentence is: Propofol caused a robust linear concentration-dependent attenuation of cortical power in the 76–200 Hz range and of thalamic power in the 30–200 Hz range. There is an error in the last sentence of the Results section in the Abstract. The correct sentence is: Furthermore the lowest concentration causing unconsciousness significantly reduced cortical power in the 126–200 Hz range and thalamic power in the 30–200 Hz range. There is an error in the first sentence of the Conclusions section in the Abstract. The correct sentence is: Propofol causes a concentration-dependent attenuation of the power of thalamocortical rhythms in the 30–200 Hz range and this effect is far more pronounced for the thalamus, where the attenuation provides a robust correlate of the hypnotic action of propofol.
منابع مشابه
Attenuation of High-Frequency (50-200 Hz) Thalamocortical EEG Rhythms by Propofol in Rats Is More Pronounced for the Thalamus than for the Cortex
BACKGROUND Thalamocortical EEG rhythms in gamma (30-80 Hz) and high-gamma (80-200 Hz) ranges have been linked to arousal and conscious processes. To test the hypothesis that general anesthetics attenuate these rhythms, we characterized the concentration-effect relationship of propofol on the spectral power of these rhythms. In view of the ongoing debate about cortex versus thalamus as the prima...
متن کاملPartial antagonism of propofol anaesthesia by physostigmine in rats is associated with potentiation of fast (80-200 Hz) oscillations in the thalamus.
BACKGROUND Positron emission tomography studies in human subjects show that propofol-induced unconsciousness in humans is associated with a reduction in thalamic blood flow, suggesting that anaesthesia is associated with impairment of thalamic function. A recent study showed that antagonism of propofol-induced unconsciousness by the anticholinesterase physostigmine is associated with a marked i...
متن کاملThalamocortical control of propofol phase-amplitude coupling
The anesthetic propofol elicits many different spectral properties on the EEG, including alpha oscillations (8-12 Hz), Slow Wave Oscillations (SWO, 0.1-1.5 Hz), and dose-dependent phase-amplitude coupling (PAC) between alpha and SWO. Propofol is known to increase GABAA inhibition and decrease H-current strength, but how it generates these rhythms and their interactions is still unknown. To inve...
متن کاملThe Histological Evidences for Developmental Alternations in the Transmitting Time of Impulses along the Thalamocortical Tract
Change in transmitting time of impulses along axons is traditionally attributed to two parameters: the myelin formation and the diameter of neurite, both rising during the postnatal development. In the previous study, we showed that conduction velocity of the fibers projecting from the thalamus to the layer IV of the somatosensory (barrel) cortex increases as a function of age. However, the con...
متن کاملHigh thalamocortical theta coherence in patients with neurogenic pain
Patients with severe and chronic neurogenic pain are known to exhibit excess EEG oscillations in the 4- to 9-Hz theta frequency band in comparison with healthy controls. The generators of these excess EEG oscillations are localized in the cortical pain matrix. Since cortex and thalamus are tightly interconnected anatomically, we asked how thalamic activity and EEG are functionally related in th...
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عنوان ژورنال:
دوره 10 شماره
صفحات -
تاریخ انتشار 2015